• Users Online: 383
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
Year : 2019  |  Volume : 17  |  Issue : 2  |  Page : 173-181

Role of diffusion-weighted MRI in evaluation of patients with salivary gland tumors

1 Department of Radiology, Faculty of Medicine, Al Azhar University, Cairo, Egypt
2 Department of General Surgery, Faculty of Medicine, Al Azhar University, Cairo, Egypt

Correspondence Address:
Mohammed S Elfeshawy
Department of Radiology, Faculty of Medicine, Al Azhar University, Cairo
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/AZMJ.AZMJ_49_19

Rights and Permissions

Background and objectives Diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) values give appreciable information about tumor cellularity with tissue contrast between the active and necrotic areas within the tumor. Aim of the work The aim of this study was to investigate the capacity of diffusion MRI to predict benign and malignant salivary gland tumors, using ADC value and DWI. Patients and methods This study included 40 patients (24 male and 16 female). Sixteen patients had malignant lesions and 24 had benign ones. The DWI was obtained with b values including 0 and 800 mm2/s. The ADC was generated by measuring identical images at different b values and represented as ADC map, from which the ADC value was calculated. This was a prospective randomized controlled trial. Informed consent was obtained from parents or guardians. Results The absolute ADC value of lesions was significantly different between benign and malignant salivary gland tumors (P<0.001). The sensitivity of ADC in differentiating benign from malignant lesions in our study was 93.7%, indicating a high true positive rate. Hence, if the average ADC is below 0.85×10−3 mm2/s, there is high probability that the mass will be malignant with high specificity of 95.8%. Results revealed that the mean ADC values of benign and malignant salivary gland tumors were 1.33±0.46×10 and 0.65±0.21×10−3 mm2/s, respectively. The mean ADC value of benign lesions was significantly higher than that of malignant lesions. Conclusion The use of DWI and ADC values can provide better assessment of salivary gland tumors and predict benign and malignant lesions.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded54    
    Comments [Add]    

Recommend this journal