|LETTER TO THE EDITOR
|Year : 2019 | Volume
| Issue : 3 | Page : 319
Seroprevalence of leptospirosis among people in Shabramant Village, Egypt
Mahmood D Al-Mendalawi
Paediatrics and Child Health, Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq
|Date of Submission||09-Mar-2019|
|Date of Decision||27-Mar-2019|
|Date of Acceptance||17-Jun-2019|
|Date of Web Publication||26-Nov-2019|
Mahmood D Al-Mendalawi
PO Box 55302, Baghdad Post Office, Baghdad
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Al-Mendalawi MD. Seroprevalence of leptospirosis among people in Shabramant Village, Egypt. Al-Azhar Assiut Med J 2019;17:319
I read with great interest the study by Elzahaby et al.  published in the April to June 2018 issue of the Al-Azhar Assiut Medical Journal. On employing microagglutination test (MAT), the authors found leptospirosis to be common among the studied cohort (44%) . I assume that such finding ought to be taken cautiously. This is based on the presence of the following methodological limitations related to the tool employed to diagnose leptospirosis. It is explicit that MAT takes several days before the results become positive after the onset of illness. Moreover, MAT requires skilled handling and also needs the maintenance of live Leptospira cells representing all serogroups . Currently, real-time PCR testing of LipL32 antigen provides the earliest detection of pathogenic Leptospira in the body with 100% specificity . I assume that if Elzahaby et al.  employed PCR in the methodology instead of MAT, more accurate results might be obtained. Despite that limitation, the worryingly high reported leptospirosis prevalence (44%), which is nearly comparable to 49.7% previously reported by Samir et al. , necessitates implementation of strict public health measure to counteract this serious zoonotic infection in Egypt.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Elzahaby AA, Zaky S, Hafez Hassanain NA, Hassan ESR, Hafez Hassanain MA, Hegazy M et al.
Seroprevalence of leptospirosis among people in Shabramant Village, Egypt. Al-Azhar Assiut Med J 2018; 16:168–175. [Full text]
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Gurumurthy K, Narasimha HB, Wyawahare M, Biswal N. Leptospirosis: a diagnostic conundrum. Trop Doct 2018; 48:306–309.
Samir A, Soliman R, El-Hariri M. Leptospirosis in animals and human contacts in Egypt: broad range surveillance. Rev Soc Bras Med Trop 2015; 48:272–277.