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Year : 2022  |  Volume : 20  |  Issue : 3  |  Page : 294-298

Fetal hemoglobin as a predictor in cases of pre-eclampsia

1 Abo El Mahmoudya Hospital, El Behaira, Egypt
2 Department of Obstetricsï Gynecology, Faculty of Medicine, Alazhar University, Cairo, Egypt
3 Department of Clinical Pathology, Faculty of Medicine, Alazhar University, Cairo, Egypt

Correspondence Address:
BSc Ahmed M.A. Elrefaei
Department of Obstetrics and Gynecology, El Mahmoudya General Hospital, Alexandria University, El Behaira
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/azmj.azmj_113_20

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Background and Aim Fetal hemoglobin (Hb) has been described as a new predictive biomarker for pre-eclampsia and has also been hypothesized to be a causative factor. Interestingly, the heme scavenger and antioxidant α-microglobulin increases in parallel with fetal Hb. The aim was to measure the level of fetal Hb in the serum of pregnant women with pre-eclampsia. Patients and methods This a prospective study that was conducted on 100 pregnant women selected from the Obstetrics and Gynecology Department of Al-Hussein University Hospital. Results There was a significant increase in fetal Hb in the patient group more than the control group. The fetal Hb shows a high sensitivity, specificity, and accuracy in prediction of pre-eclampsia and eclampsia. Conclusion Fetal Hb was significantly higher in patients with eclampisa and pre-eclampsia. Moreover, it can be used as a predictive marker for both eclampisa and pre-eclampsia.

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