| ORIGINAL ARTICLE |
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| Year : 2022 | Volume
: 20
| Issue : 3 | Page : 294-298 |
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Fetal hemoglobin as a predictor in cases of pre-eclampsia
Ahmed M.A. Elrefaei1, Abdel M.M Zakarya2, Ahmed O Abdel Motaal2, Ahmed A Assem3
1 Abo El Mahmoudya Hospital, El Behaira, Egypt
2 Department of Obstetricsï Gynecology, Faculty of Medicine, Alazhar University, Cairo, Egypt
3 Department of Clinical Pathology, Faculty of Medicine, Alazhar University, Cairo, Egypt
Correspondence Address:
BSc Ahmed M.A. Elrefaei
Department of Obstetrics and Gynecology, El Mahmoudya General Hospital, Alexandria University, El Behaira
Egypt
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/azmj.azmj_113_20
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Background and Aim Fetal hemoglobin (Hb) has been described as a new predictive biomarker for pre-eclampsia and has also been hypothesized to be a causative factor. Interestingly, the heme scavenger and antioxidant α-microglobulin increases in parallel with fetal Hb.
The aim was to measure the level of fetal Hb in the serum of pregnant women with pre-eclampsia.
Patients and methods This a prospective study that was conducted on 100 pregnant women selected from the Obstetrics and Gynecology Department of Al-Hussein University Hospital.
Results There was a significant increase in fetal Hb in the patient group more than the control group. The fetal Hb shows a high sensitivity, specificity, and accuracy in prediction of pre-eclampsia and eclampsia.
Conclusion Fetal Hb was significantly higher in patients with eclampisa and pre-eclampsia. Moreover, it can be used as a predictive marker for both eclampisa and pre-eclampsia.
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